<p style="box-sizing: border-box; margin: 0px 0px 1.25rem; padding: 0px; font-family: Georgia, 'Times New Roman', Times, serif; line-height: 1.6; text-rendering: optimizeLegibility; color: #222222; text-align: justify;">This may help understanding igf des a little. The last paragraph should answer your question about it.</p><p style="box-sizing: border-box; margin: 0px 0px 1.25rem; padding: 0px; font-family: Georgia, 'Times New Roman', Times, serif; line-height: 1.6; text-rendering: optimizeLegibility; color: #222222; text-align: justify;">DES IGF-1<strong style="box-sizing: border-box; line-height: inherit;"> </strong>is the shorter version of the IGF-1 chain. It is five (5) times more powerful than IGF-LR3 and ten (10) times more powerful than regular base IGF-1. The half-life for DES is about 20-30 minutes, which means this is a very delicate chain. Therefore, administration should only be done at the site where you want to see muscle growth. DES has the ability to stimulate muscle hyperplasia better than LR3. In simple terms, it’s best used for site injections, rather than overall growth.</p><p style="box-sizing: border-box; margin: 0px 0px 1.25rem; padding: 0px; font-family: Georgia, 'Times New Roman', Times, serif; line-height: 1.6; text-rendering: optimizeLegibility; color: #222222; text-align: justify;">In addition, <span style="text-decoration: underline;">DES is known to bind to receptors that have been deformed by lactic acid, which is often present during workouts. This allows the DES to attach itself to a mutated receptor and signal tissue growth during training</span>. DES can be used longer and more frequently than LR3</p>